This systematic review confirms an association between tramadol use and risk of bleeding in patients on vitamin k antagonists. Evidence is too limited to assess whether this risk extends to patients on direct oral anticoagulants, and further studies are needed. When a medication works right, it boosts your health or helps you feel better. But a drug can bring on problems if it doesn't mix well with something else you put into your body, like another. Mar 6, 2018 · when taking any prescription pain medication—especially opioids—it's vital to know about all possible drug interactions.
However, caution is advised when using tramadol while taking any anticoagulant medication, such as eliquis, due to the increased risk of bleeding, although this is relatively uncommon. Oct 22, 2024 · tramadol can put you at risk for overdose and death. Even if you take your dose correctly as prescribed you are at risk for opioid addiction, abuse, and misuse that can lead to death. Talk to your healthcare provider about naloxone, a medicine for the emergency treatment of an opioid overdose.
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